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Publikationsverzeichnis von Prof. Dr. med. Harald Bär

1. Bär H#, Schopferer M#, Sharma S, Hochstein B, Kleiner H, Herrmann H, Willenbacher N (2010): Mutations in desmin's carboxy-terminal "tail"-domain severely modify biophysical filament properties. (# contributed equally); J Mol Biol. 397, 1188-98.
2. Sharma S, Mücke N, Katus HA, Herrmann H, Bär H (2009): Disease mutations in the "head" domain of the extra-sarcomeric protein desmin distinctly alter its assembly and network-forming properties. J Mol Med. 87, 1207-19.
3. Kreplak L, Bär H (2009): Severe myopathy mutations modify the nanomechanics of desmin intermediate filaments. J Mol Biol. 385, 1043-1051.
4. Schopferer M#, Bär H#, Hochstein B, Sharma S, Mücke N, Herrmann H, Willenbacher N (2009): Desmin and vimentin intermediate filament networks: Their viscoelastic properties investigated by mechanical rheometry. (# contributed equally) J Mol Biol. 388, 133-143.
5. Bär H, Sharma S, Mücke N, Kleiner H, Zentgraf H, Katus HA, Aebi U, Herrmann H (2009): Interference of amino-terminal desmin fragments with desmin filament formation. Cell Motil Cytoskeleton. 66, 986-99.
6. Bär H, Siegmund A, Wolf D, Hardt S, Katus HA, Mereles D (2009): Prevalence of asymptomatic mitral valve malformations. Clin Res Cardiol. 98, 305-309.
7. Bär H, Katus HA, Mereles D (2009): Unexpected pulsatile intracardiac mass. Int J Cardiol. 135: e52-4.
8. Bär H, Katus HA, Mereles D (2009): Biventricular involvement in transient apical ballooning syndrome (Takotsubo cardiomyopathy). Int J Cardiol. 133: e79-e80.
9. Bär H, Katus HA, Mereles D (2009): Accessory mitral valve as a potential source of cardioembolism. Int J Cardiol. 131: e76-e77.
10. Strach K, Sommer T, Grohé C, Meyer C, Fischer D, Walter MC, Vorgerd M, Reilich M, Bär H, Reimann J, Reuner U, Germing A, Goebel HH, Lochmüller H, Wintersperger B, Schröder R (2008): Clinical, genetic, and cardiac magnetic resonance imaging findings in primary desminopathies. Neuromuscul Disord. 18:475-82.
11. Niebruegge S, Nehring A, Bär H, Zweigerdt R, Lehmann J (2008): Cardiomyocyte production in mass suspension culture: Embryonic stem cells as a source for great amounts of functional cardiomyocytes. Tissue Eng Part A. 14:1591-601.
12. Geiger SK#, Bär H#, Ehlermann P, Wälde S, Rutschow D, Zeller R, Ivandic BT, Zentgraf H, Katus HA, Herrmann H, Weichenhan D (2008): Incomplete nonsense-mediated decay of mutant lamin A/C mRNA provokes dilated cardiomyopathy and ventricular tachycardia. (# contributed equally) J Mol Med. 86:281-9.
13. Herrmann H, Bär H, Kreplak L, Strelkov SV, Aebi U (2007): Intermediate filaments: from cell architecture to nanomechanics. Nat Rev Mol Cell Biol. 8:1-12.
14. Bär H, Mücke N, Katus HA, Aebi U, Herrmann H (2007): Assembly defects of disease mutants carrying small deletions in the coiled-coil domain are rescued by wild type desmin. J Struct Biol. 158:107-15.
15. Bär H, Goudeau B, Wälde S, Casteras-Simon M, Mücke N, Shatunov A, Goldberg YP, Holton JL, Eymard B, Katus HA, Fardeau M, Goldfarb L, Vicart P, Herrmann H (2007): Conspicuous involvement of desmin tail mutations in diverse cardiac and skeletal myopathies. Human Mutation 28:374-86.
16. Bär H, Mereles D, Libicher M, Katus HA (2007): Lariat-like Sarcoma Infiltration of the Left Atrium. Int J Cardiol. 116:e51-2.
17. Bär H, Mücke N, Ringler P, Müller SA, Kreplak L, Katus HA, Aebi U, Herrmann H (2006): Impact of Disease Mutations on the Desmin Filament Assembly Process. J Mol Biol. 360:1031-42.
18. Bär H, Kostareva A, Sjöberg G, Sejersen T, Katus HA, Herrmann H (2006): Forced expression of desmin and desmin mutants in cultured cells: Impact of myopathic missense mutations in the central coiled-coil domain on network formation. Exp Cell Res. 312:1554-65.
19. Bär H, Mücke N, Kostareva A, Sjöberg G, Aebi U, Herrmann H (2005): Severe muscle-disease causing desmin mutations interfere with in vitro filament assembly at distinct stages. Proc Natl Acad Sci USA. 102:15099-104.
20. Kreplak L, Bär H, Leterrier JF, Herrmann H, Aebi U (2005): Intermediate filaments are mechanical shock absorbers. J Mol Biol. 354: 569-577.
21. Bär H, Goudeau B, Fischer D, Kley RA, Clemen CS, Vicart P, Herrmann H, Vorgerd M, Schröder R (2005): Pathogenic effects of a novel heterozygous R350P desmin mutation on the assembly of desmin intermediate filaments in vivo and in vitro. Hum Mol Genet. 14:1251-60.
22. Bär H, Strelkov SV, Sjöberg G, Aebi U, Herrmann H (2004): The biology of desmin filaments: how do mutations affect their structure, assembly and organization? J Struct Biol. 148(2):137-52.
23. Bär H, Kreuzer J, Cojoc A, Jahn L (2003): Upregulation of embryonic transcription factors in right ventricular hypertrophy. Basic Res Cardiol. 98:285-94.
24. Bär H, Wende P, Watson L, Denger S, van Eys G, Kreuzer J, Jahn L (2002): Smoothelin is an indicator of reversible phenotype modulation of smooth muscle cells in balloon-injured rat carotid arteries. Basic Res Cardiol. 97:9-16.
25. Bär H, Bea F, Blessing E, Watson L, Wende P, Kreuzer J, Kübler W, Jahn L (2001): Phosphorylation of cytokeratin 8 and 18 in human vascular smooth muscle cells of atherosclerotic lesions and umbilical cord vessels. Basic Res Cardiol. 96:50-8.
26. Bär H, Mereles D, Grünig E, Kuecherer H (2001): Images in echocardiography. Exaggerated pectinate muscles mimicking multiple left atrial appendage thrombi. Eur J Echocardiogr. 2:131.
27. Bea F, Bär H, Watson L, Blessing E, Kübler W, Kreuzer J, Jahn L (2000): Cardiac alpha-actin in smooth muscle cells: detection in umbilical cord vessels and in atherosclerotic lesions. Basic Res Cardiol. 95:106-13.
28. Jahn L, Bär H (1999): Cell cycle regulation. In: Apoptosis in Cardiac Biology. Edited by Schunkert H and Riegger GAJ; Kluwer Academic Publishers.
29. Bär H, Schlote W (1997): Malignant melanoma in the CNS, subtyping and immunocytochemistry. Clin Neuropathol. 16:337-45.